Magnetic Liposomal Particles for Magnetic Imaging, Sensing, and the pH‐Sensitive Delivery of Therapeutics | Zendy

Kwon YongSu | Zendy; Jang Su Jin | Zendy; Yoon Young Il | Zendy; Cho HeeSang | Zendy; Lee Hak Jong | Zendy; Cho YoungSeok | Zendy; Shin Hyun Soo | Zendy; Yoon TaeJong | Zendy

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Magnetic Liposomal Particles for Magnetic Imaging, Sensing, and the pH‐Sensitive Delivery of Therapeutics

Author(s) -

Kwon YongSu,

Jang Su Jin,

Yoon Young Il,

Cho HeeSang,

Lee Hak Jong,

Cho YoungSeok,

Shin Hyun Soo,

Yoon TaeJong

Publication year - 2016

Publication title -

particle and particle systems characterization

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.877

H-Index - 56

eISSN - 1521-4117

pISSN - 0934-0866

DOI - 10.1002/ppsc.201600041

Subject(s) - liposome , drug delivery , conjugated system , nanotechnology , computer science , in vitro , computational biology , chemistry , materials science , biology , biochemistry , physics , nuclear magnetic resonance , polymer

To maintain magnetic properties, physical properties, and bio‐applicability, a liposomal structure is introduced to the magnetic MNP@ m SiO 2 (MagLipo). EGFR‐antibody‐conjugated MagLipo is successfully applied for T 2 ‐ w imaging and magnetic sensing after specific targeting to BxPC3 pancreatic cancer. Furthermore, the MagLipo carrying a therapeutic drug and gene shows a high therapeutic effect with drug release in a pH‐sensitive manner in vitro.

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