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Pomegranate‐Structured Electrosprayed Microspheres for Long‐Term Controlled Drug Release
Author(s) -
Zhao Xin,
Hu Changmin,
Pan Guoqing,
Cui Wenguo
Publication year - 2015
Publication title -
particle and particle systems characterization
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 56
eISSN - 1521-4117
pISSN - 0934-0866
DOI - 10.1002/ppsc.201400199
Subject(s) - microsphere , drug delivery , nanoparticle , term (time) , core (optical fiber) , computer science , service (business) , drug , controlled release , nanotechnology , chemistry , chemical engineering , materials science , business , medicine , engineering , pharmacology , physics , telecommunications , quantum mechanics , marketing
Pomegranate‐structured composite microspheres composed of core mesoporous silica nanoparticles capped by a poly( l ‐lactide) shell are prepared via one‐step electrospraying, which releases encapsulated model anti‐inflammatory drugs for up to 70 d and inhibits proliferation against macrophages over the long release period.