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Drug Delivery: Multifunctional Polymer‐Coated Carbon Nanotubes for Safe Drug Delivery (Part. Part. Syst. Charact. 4/2013)
Author(s) -
Moore Thomas L.,
Pitzer Joshua E.,
Podila Ramakrishna,
Wang Xiaojia,
Lewis Robert L.,
Grimes Stuart W.,
Wilson James R.,
Skjervold Even,
Brown Jared M.,
Rao Apparao,
Alexis Frank
Publication year - 2013
Publication title -
particle and particle systems characterization
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 56
eISSN - 1521-4117
pISSN - 0934-0866
DOI - 10.1002/ppsc.201370011
Subject(s) - carbon nanotube , drug delivery , ethylene glycol , polymer , nanotechnology , materials science , paclitaxel , drug , chemistry , organic chemistry , pharmacology , composite material , surgery , medicine , chemotherapy
Poly(lactide)‐co‐poly(ethylene glycol) coated carbon nanotubes are used for controlled delivery of paclitaxel. Thomas Moore and co‐workers on page 365 report multifunctional polymer coated carbon nanotubes coated with biodegradable and biocompatible polymers to encapsulate and deliver drugs for a prolonged period of time. Furthermore, the coatings reduce in vitro cytotoxicity and in vivo systemic toxicity of carbon nanotubes, which is critical for intravenous administration. Image credit: Robert R. Johnson (University of Pennsylvania)