Fabrication of pH‐Tunable Calcium Phosphate Nanocapsules via Dendrimer‐Templated Assembly for Intracellular Lysosomal Release of Drugs | Zendy

Khandare Jayant J. | Zendy; JalotaBadhwar Archana | Zendy; Taneja Neetika | Zendy; Mascarenhas Russel R. | Zendy; Vadodaria Karan | Zendy; Zope Khushbu R. | Zendy; Banerjee Shashwat S. | Zendy

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Fabrication of pH‐Tunable Calcium Phosphate Nanocapsules via Dendrimer‐Templated Assembly for Intracellular Lysosomal Release of Drugs

Author(s) -

Khandare Jayant J.,

JalotaBadhwar Archana,

Taneja Neetika,

Mascarenhas Russel R.,

Vadodaria Karan,

Zope Khushbu R.,

Banerjee Shashwat S.

Publication year - 2013

Publication title -

particle and particle systems characterization

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.877

H-Index - 56

eISSN - 1521-4117

pISSN - 0934-0866

DOI - 10.1002/ppsc.201300034

Subject(s) - nanocapsules , dendrimer , nanotechnology , chemistry , drug delivery , polymer , dissolution , materials science , polymer chemistry , organic chemistry , nanoparticle

A pH‐responsive dendrimer templated polymer‐calcium phosphate core shell nanostructure is developed. Upon exposure to cellular lysosomal pH, a guest anticancer drug is released from the nanocapsule by dissolution of the CaP shell. Such a stimuli responsive carrier enables on‐demand controlled release of drugs in acidic organelles.

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