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Thermo‐Responsive Multi‐Cargo Core Shell Particles
Author(s) -
Nollet Maxime,
Depardieu Martin,
Destribats Mathieu,
Backov Rénal,
Schmitt Véronique
Publication year - 2013
Publication title -
particle and particle systems characterization
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 56
eISSN - 1521-4117
pISSN - 0934-0866
DOI - 10.1002/ppsc.201200032
Subject(s) - core (optical fiber) , shell (structure) , materials science , nanotechnology , composite material
Combining formulation of particle‐stabilized water‐in‐oil‐in‐water emulsion and in situ sol‐gel chemistry, original monodisperse thermo‐responsive capsules able to encapsulate at once hydrophilic and hydrophobic drugs are synthesized. Due to the presence of a stiff shell, the release is provoked by increasing the temperature above the wax melting point. The solid‐to‐liquid transition induces a volume expansion responsible for the capsule rupture.