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Investigation of air plasma generated by surface microdischarge for decellularized porcine aortic valve leaflets modification
Author(s) -
Lu Chen,
Dai Jinchi,
Dong Nianguo,
Zhu Yu,
Xiong Zilan
Publication year - 2020
Publication title -
plasma processes and polymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 74
eISSN - 1612-8869
pISSN - 1612-8850
DOI - 10.1002/ppap.202000100
Subject(s) - decellularization , surface modification , absorbance , materials science , ultimate tensile strength , microstructure , plasma , irradiation , composite material , biomedical engineering , analytical chemistry (journal) , chemistry , chromatography , medicine , scaffold , physics , quantum mechanics , nuclear physics
In this study, the surface microdischarge (SMD) device was used to modify the mechanical properties of decellularized porcine aortic valve leaflets (DPAVL). It was found that SMD treatment under NO x mode considerably improved the ultimate tensile strength and the Young's modulus of DPAVL, whereas treatment under O 3 mode had no effect. The absorbance band peak at ~1,375 cm −1 , measured by Fourier‐transform infrared spectrometer, increased with treatment time in the freeze‐dried DPAVL group under NO x mode treatment. The microstructure was not destroyed and blood compatibility test showed no toxicity. The reaction between plasma‐activated species and the DPAVL and the pH change, other than temperature/UV irradiation, plays a major role. All of the results indicate that cold atmospheric plasma treatment seems to be a potential alternative for DPAVL modification.