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A measurement method for determining the correlation between the amount of haemolysis and the electric current in low‐temperature plasma treatment
Author(s) -
Miyamoto Kenji,
Ikehara Yuzuru
Publication year - 2019
Publication title -
plasma processes and polymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 74
eISSN - 1612-8869
pISSN - 1612-8850
DOI - 10.1002/ppap.201800142
Subject(s) - haemolysis , plasma , current (fluid) , electric current , chemistry , materials science , analytical chemistry (journal) , chromatography , thermodynamics , medicine , physics , immunology , quantum mechanics
We have developed a low‐temperature plasma apparatus as a surgical device for haemostasis. A quantitative measurement method and system that analyses the relationship between the properties of low‐temperature plasma and blood components are necessary to evaluate the performance and safety of plasma apparatuses. In a previous study, we revealed that low‐temperature plasma haemolyses erythrocytes, and the released haemoglobin contribute to clot formation; haemolysis by low‐temperature plasma occurs when the value of the current originating from low‐temperature plasma exceeds a certain threshold. In the current study, we examined the correlation between the haemoglobin concentration and the electric current value through experiments using our improved measurement system. We propose a method to control the haemolysis effect by adjusting the plasma current value.