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Surface modification of polysulfone hollow fiber membrane for extracorporeal membrane oxygenator using low‐temperature plasma treatment
Author(s) -
Zheng Zhi,
Wang Weiping,
Huang Xin,
Fan Wenling,
Li Lei
Publication year - 2018
Publication title -
plasma processes and polymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 74
eISSN - 1612-8869
pISSN - 1612-8850
DOI - 10.1002/ppap.201700122
Subject(s) - polysulfone , membrane , materials science , fourier transform infrared spectroscopy , surface modification , hollow fiber membrane , protein adsorption , chemical engineering , permeation , adsorption , polymer , fiber , composite material , chemistry , organic chemistry , biochemistry , engineering
The surface of polysulfone (PSF) hollow fiber membranes (HFMs) was modified to improve the hemocompatibility of pristine PSF membrane for use in extracorporeal membrane oxygenators using low‐temperature plasma treatment. Acrylic acid (AA) with heparin, 2‐methacryloyloxyethyl phosphorylcholine (MPC), and collagen were grafted on the PSF surface to prepare PSF‐AA‐Hep, PSF‐MPC, and PSF‐Col membranes, respectively. The surface‐modified membranes were analyzed by Fourier transform infrared spectroscopy (FTIR), UV‐visible spectrophotometry (UVS), X‐ray photoelectron spectroscopy (XPS), critical water permeability pressure (CWPP), and scanning electron microscopy (SEM). Protein adsorption and platelet adhesion experiments showed that the hemocompatibility of surface‐modified PSF membranes was significantly improved. Additionally, O 2 and CO 2 gas permeation experiments indicated that the excellent gas transmission properties of PSF membrane had been preserved. Thus, the modified membrane materials can meet the requirement for commercial respiratory assist devices.