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Histological and Nuclear Medical Comparison of Inflammation After Hemostasis with Non‐Thermal Plasma and Thermal Coagulation
Author(s) -
Ueda Masashi,
Yamagami Daiki,
Watanabe Keiko,
Mori Asami,
Kimura Hiroyuki,
Sano Kohei,
Saji Hideo,
Ishikawa Kenji,
Hori Masaru,
Sakakita Hajime,
Ikehara Yuzuru,
Enomoto Shuichi
Publication year - 2015
Publication title -
plasma processes and polymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 74
eISSN - 1612-8869
pISSN - 1612-8850
DOI - 10.1002/ppap.201500099
Subject(s) - hemostasis , inflammation , coagulation , medicine , chemistry , pathology
The objective of this study is to examine the invasiveness of hemostasis by non‐thermal plasma (NTP) compared with hemostasis by thermal coagulation (TC). The inflammation recovery process after hemostasis by TC and NTP was compared by using histological methods and nuclear medical molecular imaging. The necrotic areas in the NTP group disappeared after 5 days, whereas they remained 15 days after hemostasis in the TC group. The accumulation of 2‐deoxy‐2‐[ 18 F]fluoro‐ d ‐glucopyranose ( 18 F‐FDG), which reflects the existence of inflammatory cells, was higher in the TC group than in the NTP group on day 15. Thus, this study indicates that hemostasis by NTP is less inflammatory than TC. This report is the first to evaluate inflammation that occurred after hemostasis with medical devices noninvasively.