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In Vitro Susceptibility of Multidrug Resistant Skin and Wound Pathogens Against Low Temperature Atmospheric Pressure Plasma Jet (APPJ) and Dielectric Barrier Discharge Plasma (DBD)
Author(s) -
Daeschlein Georg,
Napp Matthias,
von Podewils Sebastian,
Lutze Stine,
Emmert Steffen,
Lange Anja,
Klare Ingo,
Haase Hermann,
Gümbel Denis,
von Woedtke Thomas,
Jünger Michael
Publication year - 2014
Publication title -
plasma processes and polymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 74
eISSN - 1612-8869
pISSN - 1612-8850
DOI - 10.1002/ppap.201300070
Subject(s) - multiple drug resistance , in vitro , plasma medicine , antimicrobial , microbiology and biotechnology , dielectric barrier discharge , atmospheric pressure plasma , antibiotics , antibiotic resistance , plasma , materials science , chemistry , biology , dielectric , biochemistry , physics , optoelectronics , quantum mechanics
Plasma medicine has become an emerging field in medical sciences since cold plasma has demonstrated important antimicrobial properties. As microbial plasma susceptibility data yet are not available, the susceptibility of 194 wound isolates exhibiting multiple antibiotic resistance was tested in vitro to CP and correlated with inhibition zones. Inhibition zones increased in parallel with the number of antibiotic classes to which the tested strain exhibit resistance. CP exhibited strong antimicrobial efficacy against most important clinical skin and wound pathogens in vitro irrespective of multidrug resistance.