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Antimicrobial Activity and Cyto‐Compatibility of Plasma Polymerized Zinc Acetylacetonate Thin Films
Author(s) -
Malzahn Kerstin,
Duque Luis,
Ciernak Peter,
Wiesenmüller Steffi,
Bender Katja,
Förch Renate
Publication year - 2013
Publication title -
plasma processes and polymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 74
eISSN - 1612-8869
pISSN - 1612-8850
DOI - 10.1002/ppap.201200106
Subject(s) - zinc , plasma polymerization , polymerization , inductively coupled plasma , thin film , materials science , plasma , aqueous solution , analytical chemistry (journal) , nuclear chemistry , monomer , chemistry , chemical engineering , nanotechnology , polymer , metallurgy , chromatography , composite material , organic chemistry , physics , quantum mechanics , engineering
Plasma polymerized thin films deposited from zinc acetylacetonate in a low pressure RF capacitively coupled plasma reactor have been studied to correlate the zinc content to the metal ion release properties, antimicrobial activity and cytocompatibility. Zinc content and zinc release properties were studied using inductively coupled plasma optical emission spectroscopy (ICP‐OES) and results were correlated to those from different standard methods of surface analysis. The coatings were shown to act as a zinc reservoir, allowing for a fast release of zinc within a few hours of being in contact with aqueous solution. For all films studied a log 10 6 reduction in the growth of Staphylococcus aureus was observed. The results show the films to be cyto‐compatible towards NIH 3T3 mammalian cells up to a zinc content of about 5 µg/cm 2 .