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Effects of Low‐Temperature Atmospheric Air Plasmas on the Activity and Function of Human Lymphocytes
Author(s) -
Shi XingMin,
Zhang GuanJun,
Yuan YuKang,
Ma Yue,
Xu GuiMin,
Yang Yun
Publication year - 2008
Publication title -
plasma processes and polymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 74
eISSN - 1612-8869
pISSN - 1612-8850
DOI - 10.1002/ppap.200700174
Subject(s) - electrode , plasma , chemistry , peripheral blood , nucleic acid , atmospheric pressure plasma , biophysics , function (biology) , analytical chemistry (journal) , materials science , biochemistry , biology , chromatography , immunology , microbiology and biotechnology , physics , quantum mechanics
Samples of peripheral blood lymphocytes from 20 healthy adult volunteers were treated by using low‐temperature plasmas produced by DBD to investigate their activity and function change as a result of plasma exposure. When the lymphocytes were more than 5 cm away from the electrode center or when the treatment time was shorter than 5 s, their activity and function did not significantly change. When the lymphocytes were less than 5 cm away from the electrode center, and the treatment time was longer than 5 s, the activity and function was significantly reduced. Furthermore, plasma action resulted in the protein, nucleic acid and K + leakage from lymphocytes, and therefore in the apoptosis of lymphocytes.
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