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Effect of Dielectric Barrier Discharge Plasma on the Attachment and Proliferation of Osteoblasts Cultured over Poly( ε ‐caprolactone) Scaffolds
Author(s) -
Yildirim Eda D.,
Ayan Halim,
Vasilets Victor N.,
Fridman Alexander,
Guceri Selcuk,
Sun Wei
Publication year - 2008
Publication title -
plasma processes and polymers
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.644
H-Index - 74
eISSN - 1612-8869
pISSN - 1612-8850
DOI - 10.1002/ppap.200700041
Subject(s) - surface energy , dielectric barrier discharge , adhesion , osteoblast , contact angle , materials science , surface roughness , biocompatibility , plasma , cell adhesion , surface finish , chemical engineering , biophysics , chemistry , composite material , dielectric , in vitro , optoelectronics , biochemistry , physics , quantum mechanics , biology , metallurgy , engineering
We report the use of DBD plasma to improve the osteoblast cells adhesion and proliferation on PCL scaffolds. The effects of plasma treatment were characterized by surface energy, surface topography, and surface biocompatibility. The PCL film treated for 5 min showed the highest degree of total surface energy, mouse osteoblast cell proliferation and surface roughness. It is demonstrated that the oxygen plasma treatment not only enhances the hydrophilicity and increases solid surface energy, surface roughness of PCL but also improves the initial attachment and the proliferation of osteoblasts on the PCL substrate.