A partially testable, predictive model of psychosocial factors in the etiology of cervical cancer i. Biological, psychological and social aspects

The current research in the biological, psychological and social domains of cervical cancer are reviewed. Research related to each domain is critically reviewed and summarized. The research so far conducted in each domain is extended by suggestions for future, integrative directions. An overview is given of these three areas pointing to the likelihood of association with cervical cancer for each of the factors reviewed in each domain. Estimated likelihoods of association were based upon both the number and quality of studies conducted. Immunological aspects of each domain may mediate some (but not all) of the effects of the factors identified. In a companion review, the immunological aspects of each domain are covered, the theoretical model is developed and a set of integrative hypotheses across domains are set forth.