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Sleep aid use during and following breast cancer adjuvant chemotherapy
Author(s) -
Moore Tiffany A.,
Berger Ann M.,
Dizona Paul
Publication year - 2011
Publication title -
psycho‐oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.41
H-Index - 137
eISSN - 1099-1611
pISSN - 1057-9249
DOI - 10.1002/pon.1756
Subject(s) - medicine , medical prescription , sedative , randomized controlled trial , sleep (system call) , breast cancer , insomnia , physical therapy , cancer , anesthesia , psychiatry , pharmacology , operating system , computer science
Background : Knowledge of sleep aid use is limited despite the high prevalence of insomnia among women before, during, and following breast cancer adjuvant chemotherapy treatments (CTX). This study's purpose was to (1) determine the frequency and characteristics of participants taking sleep aid(s); (2) identify the frequency and percentage of sleep aid use by category (prescription sedative/hypnotics, prescription anti‐depressants, prescription analgesics, prescription anti‐emetics, over‐the‐counter (OTC) analgesics, OTC cold/flu/sinus, OTC sleep, alcohol, and herbal supplements); and (3) compare sleep aid use by category in the experimental and control groups within a randomized‐controlled clinical trial (RCT). Methods : Longitudinal, descriptive, secondary RCT data analysis of women ( n =219) receiving out‐patient CTX, and at 30, 60, and 90 days following the last CTX and 1 year following CTX1. Participants recorded daily sleep aid use on a Sleep Diary. Analyses included descriptives, chi‐square, and RM‐ANOVA. Results : Approximately 20% of participants took at least one sleep aid before CTX1; usage decreased over time (12–18%); a second sleep aid was used infrequently. Prescription sedative/hypnotics (46%) and OTC analgesics (24%) were used most frequently. OTC sleep aids were most commonly used as a second aid. Prescription sedative/hypnotics [ F (7,211)=4.26, p =0.00] and OTC analgesics [ F (7,211)=2.38, p =0.023] use decreased significantly over time. Conclusions : Results reflect the natural course of CTX, recovery, and healing. Comprehensive screening for sleep–wake disturbances and sleep aid use may lead to a better understanding of the risks and benefits of pharmacologic and non‐pharmacologic interventions, and ultimately lead to selection of the safest and most effective treatment. Copyright © 2010 John Wiley & Sons, Ltd.