Open AccessPhotogeneration of “clickable” surface‐bound polymer scaffolds
Author(s) -
Carroll Gregory T.,
Rengifo Hernan R.,
Grigoras Cristian,
Mammana Angela,
Turro Nicholas J.,
Koberstein Jeffrey T.
Publication year - 2017
Publication title -
journal of polymer science part a: polymer chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.768
H-Index - 152
eISSN - 1099-0518
pISSN - 0887-624X
DOI - 10.1002/pola.28485
Subject(s) - click chemistry , cycloaddition , alkyne , chromophore , acrylate , phthalimide , chemistry , monolayer , polymer chemistry , polymer , azide , photochemistry , bioconjugation , combinatorial chemistry , monomer , organic chemistry , catalysis , biochemistry
A photoactive self‐assembled monolayer (SAM) containing phthalimide chromophores can bind an alkyne‐terminated poly (tert‐butyl acrylate) polymer to the surface of the SAM upon exposure to UV light. The alkyne groups can then be used to bind species bearing azide groups via a Cu‐catalyzed 1,3‐dipolar cycloaddition reaction (click chemistry). The method provides a general approach to generate functionality, and in this case “clickable” functionality, to the surface of a material.