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O‐17 NMR studies on α‐diazoketones
Author(s) -
Cerioni Giovanni,
Culeddu Nicola,
Saba Antonio
Publication year - 1992
Publication title -
journal of physical organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.325
H-Index - 66
eISSN - 1099-1395
pISSN - 0894-3230
DOI - 10.1002/poc.610050706
Subject(s) - chemistry , substituent , aryl , chemical shift , alkyl , spectral line , nmr spectra database , inductive effect , carbon 13 nmr , computational chemistry , medicinal chemistry , stereochemistry , organic chemistry , physics , astronomy
The O‐17 NMR spectra of 13 α′‐alkyl‐ and aryl‐substituted α‐diazoketones were measured. The results obtained show a clear discrimination between them. A good correlation in a series of para ‐substituted α‐diazoacetophenones between O‐17 chemical shifts and both α + p and dual substituent parameters indicated a greater contribution of resonance than inductive effects.