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The effect of pressure on swern–moffatt oxidations
Author(s) -
Isaacs Neil S.,
Laila A. H.
Publication year - 1991
Publication title -
journal of physical organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.325
H-Index - 66
eISSN - 1099-1395
pISSN - 0894-3230
DOI - 10.1002/poc.610041009
Subject(s) - chemistry , swern oxidation , cyclohexanol , acetic anhydride , context (archaeology) , organic chemistry , dimethyl sulfoxide , catalysis , paleontology , biology
Rates of oxidation of cyclohexanol by dimethyl sulphoxide in conjunction both with acetic anhydride and with dicyclohexylcarbodiimide have been measured with variation of both temperature and pressure. Activation volumes were found to be −25 and −34 cm 3 mol −1 , respectively, and the absence of an αd PKIE was noted. The reaction mechanism is discussed in the context of these values.