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Determination of p K a values of fluorocompounds in water using 19 F NMR
Author(s) -
Parman Elisabeth,
Toom Lauri,
Selberg Sigrid,
Leito Ivo
Publication year - 2019
Publication title -
journal of physical organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.325
H-Index - 66
eISSN - 1099-1395
pISSN - 0894-3230
DOI - 10.1002/poc.3940
Subject(s) - chemistry , aqueous solution , analytical chemistry (journal) , range (aeronautics) , organic chemistry , materials science , composite material
Brønsted acidities of 19 fluorocompounds in the p K a range from 3.5 to 10 have been measured in aqueous solution using an approach involving absolute and relative p K a measurements with 19 F NMR. 19 F NMR has not been frequently used for determining p K a values, but it has a number of advantages, especially when relative values are considered: accurate concentrations not needed, tolerant to impurities, several compounds can be measured simultaneously, several uncertainty sources cancel out.