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The oxidation of alcohols to aldehydes and ketones with N ‐bromosuccinimide in polyethylene glycol: an experimental and theoretical study
Author(s) -
Fan JiCai,
Shang ZhiCai,
Liang Jun,
Liu XiuHong,
Liu Yang
Publication year - 2008
Publication title -
journal of physical organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.325
H-Index - 66
eISSN - 1099-1395
pISSN - 0894-3230
DOI - 10.1002/poc.1404
Subject(s) - chemistry , n bromosuccinimide , polyethylene glycol , solvent , acetophenone , organic chemistry , alcohol oxidation , alcohol , halogenation , catalysis
Oxidation of aliphatic and aromatic alcohols has been studied by using N ‐bromosuccinimide (NBS) as oxidant and polyethylene glycol (PEG) as reaction medium under mild reaction conditions. Temperature and solvent effect are studied. Theoretical study is also done with the Gaussian 98 suite of program and the calculation results are in good accordance with the experimental outcome. This system offers a very clean, convenient, environmentally benign method for the oxidation of alcohols. Copyright © 2008 John Wiley & Sons, Ltd.