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Electrochemical glycosylation in the presence of a catalytic chemical mediator
Author(s) -
Drouin Ludovic,
Compton Richard G.,
Fairbanks Antony J.
Publication year - 2008
Publication title -
journal of physical organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.325
H-Index - 66
eISSN - 1099-1395
pISSN - 0894-3230
DOI - 10.1002/poc.1388
Subject(s) - chemistry , glycosylation , electrochemistry , mediator , catalysis , combinatorial chemistry , organic chemistry , biochemistry , electrode , microbiology and biotechnology , biology
Electrochemical glycosylation of thioglycoside donors proceeds efficiently in an undivided cell in the presence of a catalytic amount of the chemical mediator (4‐bromophenyl) ammoniumyl hexachloroantimonate (BAHA). In comparison with electrochemical glycosylation alone, the use of a catalytic amount of BAHA greatly increases the rate of reaction, reduces the potential required and inhibits ester‐protecting group migrations. Copyright © 2008 John Wiley & Sons, Ltd.