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Free radical scavenging capacity of hydroxycinnamic acids and related compounds
Author(s) -
Pino Eduardo,
Campos Ana M.,
LópezAlarcón Camilo,
Aspée Alexis,
Lissi Eduardo
Publication year - 2006
Publication title -
journal of physical organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.325
H-Index - 66
eISSN - 1099-1395
pISSN - 0894-3230
DOI - 10.1002/poc.1071
Subject(s) - chemistry , radical , reactivity (psychology) , moiety , dissociation (chemistry) , oxygen radical absorbance capacity , kinetics , photochemistry , molecule , hydroxycinnamic acid , organic chemistry , antioxidant , antioxidant capacity , medicine , physics , alternative medicine , pathology , quantum mechanics
Abstract The capacity of hydroxycinnamic acid derivatives to trap peroxyl radicals was evaluated by competitive kinetics and oxygen radical absorbance capacity (ORAC) indexes, using c ‐phycocyanin and pyranine as target molecules. The pattern of results is similar in all the systems, with the reactivity of the compound determined by the bond dissociation energy (BDE) of the hydrogen atom of the phenolic moiety. However, differences in the relative reactivity are observed depending upon the employed methodology (initial rate of consumption or ORAC‐type methodology) and target molecule employed. These differences are explained in terms of the role played by secondary reactions of the initially formed phenoxyl radicals. This emphasizes the need for performing a complete kinetic analysis of the results in order to obtain meaningful evaluations of the relative reactivity of the tested compounds. Copyright © 2006 John Wiley & Sons, Ltd.