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Clozapine in treatment‐resistant schizophrenia: a patient's journey
Author(s) -
Korsavva Sofia,
Dhadesugur Seshadri
Publication year - 2019
Publication title -
progress in neurology and psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.19
H-Index - 12
eISSN - 1931-227X
pISSN - 1367-7543
DOI - 10.1002/pnp.523
Subject(s) - clozapine , polysubstance dependence , clonazepam , quetiapine , schizophrenia (object oriented programming) , psychiatry , medicine , asenapine , sertraline , psychology , substance abuse , olanzapine , anxiety , antidepressant
Treatment‐resistant schizophrenia can be very difficult to manage and here the authors discuss the treatment challenges in such a patient who has a dual diagnosis of polysubstance abuse. The patient responded to the unusual combination of clozapine, sertraline, quetiapine, valproate semisodium and clonazepam but there were difficulties with the clozapine titration and augmentation. The clinical management lessons are discussed.