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A case for adding fluvoxamine to clozapine
Author(s) -
Sharma Avneet
Publication year - 2018
Publication title -
progress in neurology and psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.19
H-Index - 12
eISSN - 1931-227X
pISSN - 1367-7543
DOI - 10.1002/pnp.516
Subject(s) - clozapine , fluvoxamine , schizophrenia (object oriented programming) , refractory (planetary science) , atypical antipsychotic , medicine , psychology , antipsychotic , psychiatry , fluoxetine , receptor , physics , astrobiology , serotonin
Treatment‐refractory schizophrenia affects at least 30% of all patients with schizophrenia. Clozapine remains the gold standard treatment as the chances of response with another non clozapine medication are very low. However, initiating and then maintaining patients on clozapine can be a challenge due to a complex titration regimen, dose‐related side‐effects and the requirement for regular monitoring. In this article, Dr Sharma describes the successful addition of fluvoxamine to clozapine in a patient to achieve a therapeutic level of clozapine.