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Continuation of clozapine during chemotherapy and a stem cell transplant
Author(s) -
Burlingham Amy,
Anandakumar Padmini,
Brownell Lisa
Publication year - 2016
Publication title -
progress in neurology and psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.19
H-Index - 12
eISSN - 1931-227X
pISSN - 1367-7543
DOI - 10.1002/pnp.434
Subject(s) - clozapine , medicine , multidisciplinary team , incidence (geometry) , chemotherapy , schizophrenia (object oriented programming) , continuation , psychiatry , intensive care medicine , nursing , physics , optics , computer science , programming language
Cancer incidence rates in the UK have increased by more than a third over the last four decades, so the likelihood of requiring concurrent chemotherapy and clozapine is increasing. In this situation clinicians are faced with a clinical conundrum: to stop clozapine and risk a psychotic relapse, or to continue clozapine and risk a potentially fatal agranulocytosis. This case report describes how a multidisciplinary team (MDT) worked together to balance the mental and physical health needs of a patient.