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Antidepressant drug interactions: evidence and clinical significance
Author(s) -
Bleakley Stephen
Publication year - 2016
Publication title -
progress in neurology and psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.19
H-Index - 12
eISSN - 1931-227X
pISSN - 1367-7543
DOI - 10.1002/pnp.429
Subject(s) - antidepressant , anxiety , depression (economics) , drug , pharmacodynamics , medicine , psychiatry , population , neuropathic pain , psychology , pharmacokinetics , pharmacology , environmental health , economics , macroeconomics
Antidepressants are widely used in the general population, primarily to treat depression but also commonly in conditions such as anxiety disorders and neuropathic pain. This article considers the significant pharmacodynamic and pharmacokinetic drug interactions of different antidepressants, whilst remembering that individual patient characteristics are of utmost importance in the prescribing decision.