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Prions, Parkinson's disease and the search for a new generation of treatments
Author(s) -
Greener Mark
Publication year - 2011
Publication title -
progress in neurology and psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.19
H-Index - 12
eISSN - 1931-227X
pISSN - 1367-7543
DOI - 10.1002/pnp.219
Subject(s) - disease , parkinson's disease , neuroscience , cytosol , medicine , biology , biochemistry , enzyme
Recent research suggests that aggregates of cytosolic proteins such as α‐synuclein may spread in a manner similar to prions in certain neurodegenerative diseases. Mark Greener explains how drugs that can reduce formation or increase clearance of these proteins may represent new treatment strategies for Parkinson's disease. Copyright © 2011 John Wiley & Sons, Ltd.