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Front Cover: Identification of Changing Ribosome Protein Compositions using Mass Spectrometry
Author(s) -
Samir Parimal,
Browne Christopher M.,
Sun Ming,
Shen Bingxin,
Li Wen,
Frank Joachim,
Link Andrew J.
Publication year - 2018
Publication title -
proteomics
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.26
H-Index - 167
eISSN - 1615-9861
pISSN - 1615-9853
DOI - 10.1002/pmic.201870181
Subject(s) - ribosome , protein biosynthesis , mass spectrometry , rna , front cover , computational biology , messenger rna , biology , translation (biology) , eukaryotic ribosome , identification (biology) , microbiology and biotechnology , chemistry , gene , biochemistry , cover (algebra) , chromatography , ecology , mechanical engineering , engineering
DOI: 10.1002/pmic.201800217 Eukaryotic cells contain different types of ribosomes that differ in their protein and RNA composition. The ribosome filter hypothesis predicts that the different ribosomes will translate specific mRNAs with differing efficiency. This allows the cells to fine tune the gene expression to different environmental conditions. It is an example of ribosomes acting as regulatory elements in translational control. Further details can be found in article number 1800217 by Samir et al.