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Inside Front Cover: Identification of Plasma Membrane Glycoproteins Specific to Human Glioblastoma Multiforme Cells Using Lectin Arrays and LC‐MS/MS
Author(s) -
Park Yae Eun,
Yeom Jeonghun,
Kim YoungSoo,
Lee Hye Jin,
Han KiCheol,
Lee SeungTaek,
Lee Cheolju,
Lee Ji Eun
Publication year - 2018
Publication title -
proteomics
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.26
H-Index - 167
eISSN - 1615-9861
pISSN - 1615-9853
DOI - 10.1002/pmic.2018700012
Subject(s) - front cover , glycoprotein , lectin , glioma , membrane glycoproteins , glioblastoma , cell , chemistry , mass spectrometry , cancer research , microbiology and biotechnology , biology , biochemistry , cover (algebra) , chromatography , mechanical engineering , engineering
DOI: 10.1002/pmic.201700302 As demonstrated by Yae Eun Park et al. in article number 1700302, lectin arrays in conjunction with label‐free quantitative mass spectrometry allowed for discovering cell surface glycoproteins to differentiate low‐ and high‐grade glioma cells (Hs683 and T98G). The cell surface glycoproteins showing significant increases in the high‐grade glioma cells could be valuable diagnostic markers and therapeutic targets for malignant gliomas.