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Inside Front Cover: Development and application of a novel recombinant Aleuria aurantia lectin with enhanced core fucose binding for identification of glycoprotein biomarkers of hepatocellular carcinoma
Author(s) -
Norton Pamela,
Comunale Mary Ann,
Herrera Harmin,
Wang Mengjun,
Houser Josef,
Wimmerova Michaela,
Romano Patrick R.,
Mehta Anand
Publication year - 2016
Publication title -
proteomics
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.26
H-Index - 167
eISSN - 1615-9861
pISSN - 1615-9853
DOI - 10.1002/pmic.201670311
Subject(s) - lectin , front cover , mannan binding lectin , chemistry , glycoprotein , hepatocellular carcinoma , biochemistry , recombinant dna , fucose , biology , cancer research , cover (algebra) , gene , mechanical engineering , engineering
DOI: 10.1002/pmic.201600064 Surface representation of rAAL N224Q complexed with Fucα1‐6GlcNAc disaccharides (in licorice). The rAAL N224Q lectin was used to find novel biomarkers of hepatocellular carcinoma. Amino acid hydrophobicity is colored from the least to the most, white to red respectively. For more details, see the article by Pamela Norton et al. on page 3126.