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Quantitative phosphoproteomic analysis of the PI3K‐regulated signaling network Florian Gnad, Jeffrey Wallin, Kyle Edgar, Sophia Doll, David Arnott, Liliane Robillard, Donald S. Kirkpatrick, Matthew P. Stokes, Ulka Vijapurkar, Georgia Hatzivassiliou, Lori S. Friedman and Marcia Belvin DOI: 10.1002/pmic.201600118 Phosphoproteome analysis of the MAPK pathway reveals previously undetected feedback mechanisms Florian Gnad, Sophia Doll, Kyung Song, Matthew P. Stokes, John Moffat, Bonnie Liu, David Arnott, Jeffrey Wallin, Lori S. Friedman, Georgia Hatzivassiliou and Marcia Belvin DOI: 10.1002/pmic.201600119 Mutations in the PI3K and MAPK pathways turn them into supervillans that drive most human cancers. Gnad et al. use mass spectrometry as their superpower to track the actions of these oncogenic villains to better understand their crimes and eventually be able to thwart them. For more details, see the articles by Florian Gnad et al. on pages 1992–1997 and 1998–2004.