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Inside front cover: In situ detection of histone variants and modifications in mouse brain using imaging mass spectrometry
Author(s) -
Lahiri Shibojyoti,
Sun Na,
SolisMezarino Victor,
Fedisch Andreas,
Ninkovic Jovica,
Feuchtinger Annette,
Götz Magdalena,
Walch Axel,
Imhof Axel
Publication year - 2016
Publication title -
proteomics
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.26
H-Index - 167
eISSN - 1615-9861
pISSN - 1615-9853
DOI - 10.1002/pmic.201670034
Subject(s) - histone , mass spectrometry , in situ , front cover , chromatin , mass spectrometry imaging , chemistry , computational biology , linker , cover (algebra) , biology , chromatography , microbiology and biotechnology , dna , biochemistry , computer science , mechanical engineering , organic chemistry , engineering , operating system
DOI: 10.1002/pmic.201500345 The image illustrates the ability of imaging mass spectrometry for in situ detection of histones, which are an integral part of chromatin that form the chromosomes. Mass spectra generated directly from tissues provide spatial information about the analytes measured in a label‐free manner. Using this technique, different variants of the linker histone H1 are mapped in mammalian brain. For details see the article by Shibojyoti Lahiri et al. on page 437.