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Phosphorylation‐dependent regulation of plant chromatin and chromatin‐associated proteins
Author(s) -
Bigeard Jean,
Rayapuram Naganand,
Pflieger Delphine,
Hirt Heribert
Publication year - 2014
Publication title -
proteomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.26
H-Index - 167
eISSN - 1615-9861
pISSN - 1615-9853
DOI - 10.1002/pmic.201400073
Subject(s) - chromatin , histone modifying enzymes , chromatin remodeling , chia pet , microbiology and biotechnology , biology , protein phosphorylation , phosphorylation , histone , histone code , non histone protein , epigenetics , genetics , dna , nucleosome , protein kinase a , gene
In eukaryotes, most of the DNA is located in the nucleus where it is organized with histone proteins in a higher order structure as chromatin. Chromatin and chromatin‐associated proteins contribute to DNA‐related processes such as replication and transcription as well as epigenetic regulation. Protein functions are often regulated by PTMs among which phosphorylation is one of the most abundant PTM. Phosphorylation of proteins affects important properties, such as enzyme activity, protein stability, or subcellular localization. We here describe the main specificities of protein phosphorylation in plants and review the current knowledge on phosphorylation‐dependent regulation of plant chromatin and chromatin‐associated proteins. We also outline some future challenges to further elucidate protein phosphorylation and chromatin regulation.