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IQuant: An automated pipeline for quantitative proteomics based upon isobaric tags
Author(s) -
Wen Bo,
Zhou Ruo,
Feng Qiang,
Wang Quanhui,
Wang Jun,
Liu Siqi
Publication year - 2014
Publication title -
proteomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.26
H-Index - 167
eISSN - 1615-9861
pISSN - 1615-9853
DOI - 10.1002/pmic.201300361
Subject(s) - isobaric process , pipeline (software) , computer science , software , isobaric labeling , proteomics , quantitative proteomics , interface (matter) , process (computing) , identification (biology) , software engineering , data mining , operating system , chemistry , biology , biochemistry , physics , botany , bubble , maximum bubble pressure method , gene , thermodynamics
Quantitative proteomics technology based on isobaric tags is playing an important role in proteomic investigation. In this paper, we present an automated software, named IQuant, which integrates a postprocessing tool of protein identification and advanced statistical algorithms to process the MS/MS signals generated from the peptides labeled by isobaric tags and aims at proteomics quantification. The software of IQuant, which is freely downloaded at http://sourceforge.net/projects/iquant/, can run from a graphical user interface and a command-line interface, and can work on both Windows and Linux systems.