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Quantum dot applications endowing novelty to analytical proteomics
Author(s) -
Wu HuiFen,
Gopal Judy,
Abdelhamid Hani Nasser,
Hasan Nazim
Publication year - 2012
Publication title -
proteomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.26
H-Index - 167
eISSN - 1615-9861
pISSN - 1615-9853
DOI - 10.1002/pmic.201200295
Subject(s) - quantum dot , proteomics , nanotechnology , mass spectrometry , materials science , chemistry , chromatography , biochemistry , gene
This review surveys all the state‐of‐art applications of quantum dots ( QD s) in conventional and modern analytical methods in proteomic studies. A brief introduction of QD s and their properties is initially presented followed by outlining the application of QD s in fluorescence, MS , imaging, and cancer‐based proteomics. The in‐depth application of QD s in MALDI ‐ MS and surface assisted laser desorption/ionization‐ MS has been elaborately discussed, summarizing the speculated mechanism behind the protein– QD s interactions during QD matrix applications leading to enhanced detection sensitivity.