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A B ovine P eptide A tlas of milk and mammary gland proteomes
Author(s) -
Bislev Stine L.,
Deutsch Eric W.,
Sun Zhi,
Farrah Terry,
Aebersold Ruedi,
Moritz Robert L.,
Bendixen Emøke,
Codrea Marius C.
Publication year - 2012
Publication title -
proteomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.26
H-Index - 167
eISSN - 1615-9861
pISSN - 1615-9853
DOI - 10.1002/pmic.201200057
Subject(s) - chemistry , biology
Proteome information resources of farm animals are lagging behind those of the classical model organisms despite their important biological and economic relevance. Here, we present a B ovine P eptide A tlas, representing a first collection of Bos taurus proteome data sets within the P eptide A tlas framework. This database was built primarily as a source of information for designing selected reaction monitoring assays for studying milk production and mammary gland health, but it has an intrinsic general value for the farm animal research community. The B ovine P eptide A tlas comprises 1921 proteins at 1.2% false discovery rate ( FDR ) and 8559 distinct peptides at 0.29% FDR identified in 107 samples from six tissues. The P eptide A tlas web interface has a rich set of visualization and data exploration tools, enabling users to interactively mine information about individual proteins and peptides, their prototypic features, genome mappings, and supporting spectral evidence.