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Computational structural analysis of protein interactions and networks
Author(s) -
Hooda Yogesh,
Kim Philip M.
Publication year - 2012
Publication title -
proteomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.26
H-Index - 167
eISSN - 1615-9861
pISSN - 1615-9853
DOI - 10.1002/pmic.201100597
Subject(s) - structural biology , systems biology , computational biology , protein–protein interaction , key (lock) , focus (optics) , modelling biological systems , protein interaction networks , computer science , biology , data science , physics , microbiology and biotechnology , ecology , optics
Protein interactions have been at the focus of computational biology in recent years. In particular, interest has come from two different communities – structural and systems biology. Here, we will discuss key systems and structural biology methods that have been used for analysis and prediction of protein–protein interactions and the insight these approaches have provided on the nature and organization of protein–protein interactions inside cells.