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FragmentationAnalyzer: An open‐source tool to analyze MS/MS fragmentation data
Author(s) -
Barsnes Harald,
Eidhammer Ingvar,
Martens Lennart
Publication year - 2010
Publication title -
proteomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.26
H-Index - 167
eISSN - 1615-9861
pISSN - 1615-9853
DOI - 10.1002/pmic.200900681
Subject(s) - fragmentation (computing) , open source , computer science , data mining , computational biology , chemistry , biology , operating system , software
A thorough understanding of the fragmentation processes in MS/MS can be a powerful tool in assessing the resulting peptide and protein identifications. We here present the freely available, open-source FragmentationAnalyzer tool (http://fragmentation-analyzer.googlecode.com) that makes it straightforward to analyze large MS/MS data sets for specific types of identified peptides, using a common set of peptide properties. This enables the detection of fragmentation pattern nuances related to specific instruments or due to the presence of post-translational modifications.