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Proteomics of lung physiopathology
Author(s) -
Miller Ingrid,
Eberini Ivano,
Gianazza Elisabetta
Publication year - 2008
Publication title -
proteomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.26
H-Index - 167
eISSN - 1615-9861
pISSN - 1615-9853
DOI - 10.1002/pmic.200800315
Subject(s) - proteome , proteomics , biological fluids , computational biology , identification (biology) , lung , biology , pathophysiology , disease , pathology , bioinformatics , medicine , chemistry , biochemistry , chromatography , botany , gene
This compilation accounts the efforts made to characterize the proteomes of lung tissues in health and disease and to recognize proteomic patterns of diseased states in the patient's biological fluids/secretions and lavage fluids. A massive amount of primary data could not lead yet to the identification of diagnostic proteomic signatures. The variability of proteomic findings associated with lung diseases suggests that a useful diagnostic index may eventually result only from the composite predictive values of a large panel of protein markers.