Premium
The analysis of Neisseria meningitidis proteomes: Reference maps and their applications
Author(s) -
Bernardini Giulia,
Braconi Daniela,
Santucci Annalisa
Publication year - 2007
Publication title -
proteomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.26
H-Index - 167
eISSN - 1615-9861
pISSN - 1615-9853
DOI - 10.1002/pmic.200700094
Subject(s) - neisseria meningitidis , pathogenicity , proteome , computational biology , biology , microbiology and biotechnology , bacteria , bioinformatics , genetics
Neisseria meningitidis is an encapsulated Gram‐negative bacterium responsible for significant morbidity and mortality worldwide. The availability of meningococcal genome sequences in combination with the rapid growth of proteomic techniques and other high‐throughput methods, provided new approaches to the analysis of bacterial system biology. This review considers the meningococcal reference maps so far published as a starting point aimed to elucidate bacterial physiology and pathogenicity, paying particular attention to proteins with potential vaccine and diagnostic applications.