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Proteomics and transfusion medicine: Future perspectives
Author(s) -
Queloz PierreAlain,
Thadikkaran Lynne,
Crettaz David,
Rossier Joel S.,
Barelli Stefano,
Tissot JeanDaniel
Publication year - 2006
Publication title -
proteomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.26
H-Index - 167
eISSN - 1615-9861
pISSN - 1615-9853
DOI - 10.1002/pmic.200600179
Subject(s) - transfusion medicine , proteomics , apheresis , abo blood group system , fresh frozen plasma , blood proteins , medicine , blood transfusion , blood product , blood preservation , intensive care medicine , platelet , chemistry , immunology , surgery , physiology , biochemistry , gene
Limited number of important discoveries have greatly contributed to the progresses achieved in the blood transfusion; ABO histo‐blood groups, citrate as anticoagulant, fractionation of plasma proteins, plastic bags and apheresis machines. Three major types of blood products are transfused to patients: red cell concentrates, platelet concentrates and fresh frozen plasma. Several parameters of these products change during storage process and they have been well studied over the years. However, several aspects have completely been ignored; in particular those related to peptide and protein changes. This review presents what has been done using proteomic tools and the potentials of proteomics for transfusion medicine.