Helicobacter pylori   immunoproteomes in case reports of rosacea and chronic urticaria | Zendy

Mini Roberta | Zendy; Figura Natale | Zendy; D'Ambrosio Chiara | Zendy; Braconi Daniela | Zendy; Bernardini Giulia | Zendy; Di Simplicio Francesca | Zendy; Lenzi Cristina | Zendy; Nuti Ranuccio | Zendy; Trabalzini Lorenza | Zendy; Martelli Paola | Zendy; Bovalini Lucia | Zendy; Scaloni Andrea | Zendy; Santucci Annalisa | Zendy

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Helicobacter pylori immunoproteomes in case reports of rosacea and chronic urticaria

Author(s) -

Mini Roberta,

Figura Natale,

D'Ambrosio Chiara,

Braconi Daniela,

Bernardini Giulia,

Di Simplicio Francesca,

Lenzi Cristina,

Nuti Ranuccio,

Trabalzini Lorenza,

Martelli Paola,

Bovalini Lucia,

Scaloni Andrea,

Santucci Annalisa

Publication year - 2005

Publication title -

proteomics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.26

H-Index - 167

eISSN - 1615-9861

pISSN - 1615-9853

DOI - 10.1002/pmic.200401094

Subject(s) - rosacea , helicobacter pylori , immunology , pathogenesis , immunoglobulin e , immune system , chronic urticaria , medicine , helicobacter pylori infection , antibody , biology , dermatology , gastroenterology , acne

Rosacea and chronic urticaria are two common skin disorders existing in idiopathic forms. A role of Helicobacter pylori bacterium infection in the aetiopathogenesis of rosacea or chronic urticaria has been suggested although still controversial. The aim of the present study was to establish a relationship between H. pylori infection and rosacea chronic urticaria by means of an immunoproteomic investigation. We analyzed immunoglobulin A (IgA)‐, IgG‐, and IgE‐mediated immune‐responses against H. pylori antigens and we identified some bacterial immunoresponsive proteins. A general IgA‐ and IgE‐mediated immune response against antioxidative bacterial proteins was observed. A correlation between the bacterial occurrence and skin diseases pathogenesis is discussed.

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