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Expanding the organismal scope of proteomics: Cross‐species protein identification by mass spectrometry and its implications
Author(s) -
Liska Adam J.,
Shevchenko Andrej
Publication year - 2003
Publication title -
proteomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.26
H-Index - 167
eISSN - 1615-9861
pISSN - 1615-9853
DOI - 10.1002/pmic.200390004
Subject(s) - proteomics , proteome , computational biology , identification (biology) , scope (computer science) , mass spectrometry , biology , bottom up proteomics , genome , chemistry , bioinformatics , protein mass spectrometry , tandem mass spectrometry , computer science , chromatography , biochemistry , ecology , gene , programming language
Due to the limited applicability of conventional protein identification methods to the proteomes of organisms with unsequenced genomes, researchers have developed approaches to identify proteins using mass spectrometry and sequence similarity database searches. Both the integration of mass spectrometry with bioinformatics and genomic sequencing drive the expanding organismal scope of proteomics.