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GLYCO‐FRAGMENT: A web tool to support the interpretation of mass spectra of complex carbohydrates
Author(s) -
Lohmann Klaus K.,
von der Lieth ClausW.
Publication year - 2003
Publication title -
proteomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.26
H-Index - 167
eISSN - 1615-9861
pISSN - 1615-9853
DOI - 10.1002/pmic.200300505
Subject(s) - fragment (logic) , interpretation (philosophy) , mass spectrum , computational biology , chemistry , web application , mass spectrometry , computer science , world wide web , biology , chromatography , algorithm , programming language
Mass spectrometry is frequently used to analyze complex oligosaccharides and glycopeptides. The spectra of glycans can be complicated and difficult to interpret without reference data. Unfortunately, no libraries of suitably pure and homogeneous standards have so far been compiled. The web-based tool GLYCO-FRAGMENT allows the generation of all theoretically possible MS relevant fragments of oligosaccharides as defined using the extended IUPAC nomenclature. The main focus of GLYCO-FRAGMENT is to support the manual assignment of all peaks contained in mass spectra of complex carbohydrates. The service is available at http://www.dkfz.de/spec/projekte/fragments/.