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Amine‐modified poly(vinyl alcohol) as a novel surfactant to modulate size and surface charge of poly(lactide‐ co ‐glycolide) nanoparticles
Author(s) -
Cella Claudia,
Martello Federico,
Ghisletti Serena,
Lenardi Cristina,
Milani Paolo,
Argentiere Simona
Publication year - 2016
Publication title -
polymer international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.592
H-Index - 105
eISSN - 1097-0126
pISSN - 0959-8103
DOI - 10.1002/pi.5122
Subject(s) - vinyl alcohol , plga , biocompatibility , pulmonary surfactant , materials science , nanoparticle , emulsion , chemical engineering , surface charge , cationic polymerization , membrane emulsification , polymer chemistry , surface modification , solvent , chemistry , organic chemistry , nanotechnology , polymer , composite material , engineering
In emulsion‐based synthesis of poly(lactide‐ co ‐glycolide) nanoparticles, different mixtures of poly(vinyl alcohol) ( PVA ) and a novel surfactant (amino‐ PVA ) were investigated to obtain cytocompatible nanoparticles with good degradability, tunable size and endosomal escape potential.