Tuning core hydrophobicity of spherical polymeric nanoconstructs for docetaxel delivery | Zendy

Di Mascolo Daniele | Zendy; Basnett Pooja | Zendy; Palange Anna Lisa | Zendy; Francardi Marco | Zendy; Roy Ipsita | Zendy; Decuzzi Paolo | Zendy

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Tuning core hydrophobicity of spherical polymeric nanoconstructs for docetaxel delivery

Author(s) -

Di Mascolo Daniele,

Basnett Pooja,

Palange Anna Lisa,

Francardi Marco,

Roy Ipsita,

Decuzzi Paolo

Publication year - 2016

Publication title -

polymer international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.592

H-Index - 105

eISSN - 1097-0126

pISSN - 0959-8103

DOI - 10.1002/pi.5072

Subject(s) - plga , polymer , polyethylene glycol , drug delivery , bioavailability , docetaxel , controlled release , nanocarriers , materials science , chemistry , nanoparticle , nanotechnology , cytotoxicity , drug carrier , combinatorial chemistry , organic chemistry , pharmacology , cancer , in vitro , biochemistry , medicine

Poly(D,L‐lactide‐ co ‐glycolic) acid (PLGA) and poly(3‐hydroxybutyrate) (P(3HB)) are used for the formulation of Docetaxel‐loaded Spherical Polymeric Nanoconstructs (SPNs), modulating their pharmaco‐related properties but maintaining similar cytotoxic efficacy.

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