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Multi‐functional heparin–biotin/heparin/calcium carbonate/calcium phosphate nanoparticles for targeted co‐delivery of gene and drug
Author(s) -
Liang Ping,
Wang ChaoQun,
Chen Hong,
Zhuo RenXi,
Cheng SiXue
Publication year - 2015
Publication title -
polymer international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.592
H-Index - 105
eISSN - 1097-0126
pISSN - 0959-8103
DOI - 10.1002/pi.4824
Subject(s) - drug delivery , doxorubicin hydrochloride , gene delivery , chemistry , hela , transfection , biochemistry , doxorubicin , in vitro , biology , gene , organic chemistry , chemotherapy , genetics
Multi‐functional heparin‐biotin/heparin/CaCO 3 /calcium phosphate/DNA/doxorubicin hydrochloride (HPB/HP/CaCO 3 /CaP/DNA/DOX) nanoparticles with pH sensitivity and tumor‐targeting properties could efficiently deliver p53 gene and a chemotherapy drug.