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A novel temperature and pH dual‐responsive hybrid hydrogel with polyhedral oligomeric silsesquioxane as crosslinker: synthesis, characterization and drug release properties
Author(s) -
Zhang Xiaojing,
Li Chong,
Hu Yuelei,
Liu Ruixue,
He Linghao,
Fang Shaoming
Publication year - 2014
Publication title -
polymer international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.592
H-Index - 105
eISSN - 1097-0126
pISSN - 0959-8103
DOI - 10.1002/pi.4757
Subject(s) - self healing hydrogels , differential scanning calorimetry , swelling , materials science , thermogravimetric analysis , methacrylate , silsesquioxane , chemical engineering , polymer chemistry , dynamic mechanical analysis , fourier transform infrared spectroscopy , polymer , thermal stability , glass transition , copolymer , composite material , physics , engineering , thermodynamics
Instead of N , N ′‐methylenebisacrylamide, octavinyl polyhedral oligomeric silsesquioxane ( OVPS ) was used as a crosslinker to copolymerize with 2‐(dimethylamino)ethyl methacrylate ( DMAEMA ) or DMAEMA and N ‐isopropylacrylamide ( NIPAM ), to prepare novel hybrid hydrogels with dual sensitivity to temperature and pH .