A novel temperature and  pH  dual‐responsive hybrid hydrogel with polyhedral oligomeric silsesquioxane as crosslinker: synthesis, characterization and drug release properties | Zendy

Zhang Xiaojing | Zendy; Li Chong | Zendy; Hu Yuelei | Zendy; Liu Ruixue | Zendy; He Linghao | Zendy; Fang Shaoming | Zendy

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A novel temperature and pH dual‐responsive hybrid hydrogel with polyhedral oligomeric silsesquioxane as crosslinker: synthesis, characterization and drug release properties

Author(s) -

Zhang Xiaojing,

Li Chong,

Hu Yuelei,

Liu Ruixue,

He Linghao,

Fang Shaoming

Publication year - 2014

Publication title -

polymer international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.592

H-Index - 105

eISSN - 1097-0126

pISSN - 0959-8103

DOI - 10.1002/pi.4757

Subject(s) - self healing hydrogels , differential scanning calorimetry , swelling , materials science , thermogravimetric analysis , methacrylate , silsesquioxane , chemical engineering , polymer chemistry , dynamic mechanical analysis , fourier transform infrared spectroscopy , polymer , thermal stability , glass transition , copolymer , composite material , physics , engineering , thermodynamics

Instead of N , N ′‐methylenebisacrylamide, octavinyl polyhedral oligomeric silsesquioxane ( OVPS ) was used as a crosslinker to copolymerize with 2‐(dimethylamino)ethyl methacrylate ( DMAEMA ) or DMAEMA and N ‐isopropylacrylamide ( NIPAM ), to prepare novel hybrid hydrogels with dual sensitivity to temperature and pH .

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