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Influence of lactic acid on degradation and biocompatibility of electrospun poly( ε ‐caprolactone) fibers
Author(s) -
Kim Eun Kyo,
Pant Hem Raj,
Hwang BoSang,
Kim Yu Kyoung,
Kim Hak Yong,
Lee Kang Min,
Park ChanHee,
Kim Cheol Sang
Publication year - 2014
Publication title -
polymer international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.592
H-Index - 105
eISSN - 1097-0126
pISSN - 0959-8103
DOI - 10.1002/pi.4626
Subject(s) - electrospinning , biocompatibility , materials science , caprolactone , chemical engineering , lactic acid , thermogravimetric analysis , biodegradation , scanning electron microscope , fiber , polyester , fourier transform infrared spectroscopy , composite number , polymer chemistry , composite material , polymer , chemistry , organic chemistry , polymerization , biology , bacteria , engineering , metallurgy , genetics
Lactic acid ( LA )‐containing electrospun poly( ε ‐caprolactone) ( PCL ) fibers show improved biocompatibility and biodegradability compared to pristine PCL fibers. Simple conversion of LA into calcium lactate by Ca( OH ) 2 treatment further improves bone compatibility of the composite fibers.