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Biocompatibility and characteristics of theophylline/carboxymethyl chitosan microspheres for pulmonary drug delivery
Author(s) -
Zhang Wei Fen,
Zhao Xin Tong,
Zhao Qing Sheng,
Zha Sheng Hua,
Liu Dong Mei,
Zheng Zeng Juan,
Li Wen Tao,
Zhou Hui Yun,
Yan Fang
Publication year - 2014
Publication title -
polymer international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.592
H-Index - 105
eISSN - 1097-0126
pISSN - 0959-8103
DOI - 10.1002/pi.4606
Subject(s) - biocompatibility , haemolysis , theophylline , drug delivery , chitosan , drug carrier , in vivo , biomedical engineering , chemistry , pharmacology , cyclodextrin , materials science , nanotechnology , medicine , chromatography , biochemistry , immunology , organic chemistry , microbiology and biotechnology , biology
Theophylline/carboxymethyl chitosan/β‐cyclodextrin microspheres made by spray drying were spherical shaped with smooth surface. It possesses good biocompability and can be used as a promising carrier for pulmonary drug delivery.